Pure Encapsulations Glycine

Your body demands glycine for some of its most critical functions: building collagen to protect joints and connective tissue, producing glutathione for antioxidant defense, and calming your nervous system so you actually sleep deep enough to recover.

The problem is that even though your body makes some glycine on its own, research shows it can't produce nearly enough to keep up with the demands of hard training. Athletes burn through it faster than almost anyone.

Pure Encapsulations Glycine delivers 1,500 mg of free-form glycine per serving in a clean, hypoallergenic capsule. It's the simplest amino acid with some of the most wide-ranging benefits for endurance athletes — from deeper sleep to stronger connective tissue to better detoxification.

Deeper, More Restorative Sleep – Glycine acts as a calming signal in your nervous system, helping lower your core body temperature and quiet brain activity to promote faster sleep onset and better sleep quality. Research shows that 3 g of glycine before bed improves sleep quality and reduces next-day fatigue — even after nights of restricted sleep.

Collagen Production for Joints and Tendons – One-third of all amino acids in collagen is glycine. It's the essential building block your body needs to synthesize and repair the connective tissue that holds your joints, tendons, and ligaments together. For athletes logging serious mileage, that structural maintenance is non-negotiable.

Supports Detoxification and Antioxidant Defense – Glycine is a precursor to glutathione, your body's most important internal antioxidant. It also supports liver and kidney function, helping your body process and clear the metabolic byproducts of hard training more efficiently.

Glycine plays a unique dual role in athletic recovery. As an inhibitory neurotransmitter, it helps your brain wind down for sleep — the single most important recovery window you have. And as a structural amino acid, it feeds collagen synthesis and supports the connective tissues that absorb the repetitive impact of endurance training.

Research also indicates glycine may help preserve muscle mass, reduce inflammation, and support creatine synthesis, which fuels short-burst power output.

How to Use Glycine

Take 3 capsules (1,500 mg), 1-2 times daily, between meals. For sleep benefits, take your evening dose about 30-60 minutes before bed.

A 3,000 mg dose (6 capsules or 2 servings) before bed aligns with the research showing improved sleep quality and reduced next-day fatigue.